A terrible pandemic outbreak suddenly grips the entire world throwing it into chaos and medical experts across the globe advise all citizens to self-isolate in order to survive. Aidan (Tyler Posey) wakes up to find himself trapped in his apartment, totally cut off the outside world and unable to reach his loved ones with infected people everywhere in his building.

His dire circumstances shift when he spots his beautiful neighbor Eva (Summer Spiro) in the apartment across the way. Communicating through written messages, their romance blooms amidst the madness. With no electricity and supplies running low, Aidan decides to take his life into his own hands and try to save them both.

Trying to maneuver unnoticed through his apartment complex, he discovers his elderly neighbor Edward (Donald Sutherland) surprisingly still alive and thrilled to have some company as he generously shares his food with Aidan. But danger lurks everywhere, even in the hands of this welcoming and seemingly harmless grandpa.